The reaction of 6-chloro-3-methoxycarbonylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxaline(5) or 3-methoxycarbonylmethylene-6-nitro-2-oxo-1,2,3,4-tetrahydroquinoxaline(6) with hydrazine hydrate gave 3-hydrazinocarbonylmethylene-2-oxo-1,2,3,4-tetrahydroquinoxalines(7, 8). The reaction of compound 7 or 8 with substituted benzaldehydes or heteroaromatic aldehydes afforded quinoxalines(9-14). Compounds showed the tautomerism between the enamine and methylene imine forms, and between the enamine, methylene imine and enaminol forms in dimethyl sulfoxide solution. The tautomer ratios were determined by the 1H NMR.
@article{ JCGMDC_2003_v47n4_345}
,title={Synthesis and Tautomerism of Novel Quinoxalines (Part II)}
,volume={4}
, url={http://dx.doi.org/10.5012/jkcs.2003.47.4.345}, DOI={10.5012/jkcs.2003.47.4.345}
, number= {4}
, journal={Journal of the Korean Chemical Society}
, publisher={Korean Chemical Society}
, author={Ho Sik, Kim
and
Kyung Ok, Choi
and
Woo Sung, Lim}
, year={2003}
, month={Aug}
TY - JOUR
T2 - Journal of the Korean Chemical Society
AU - Ho Sik, Kim
AU - Kyung Ok, Choi
AU - Woo Sung, Lim
SN - 1017-2548
TI - Synthesis and Tautomerism of Novel Quinoxalines (Part II)
VL - 47
PB - Korean Chemical Society
DO - 10.5012/jkcs.2003.47.4.345
PY - 2003
UR - http://dx.doi.org/10.5012/jkcs.2003.47.4.345
ER -
Ho Sik, K.
,
Kyung Ok, C.
,
&
Woo Sung, L.
( 2003).
Synthesis and Tautomerism of Novel Quinoxalines (Part II).
Journal of the Korean Chemical Society,
47
(4)
Korean Chemical Society.
doi:10.5012/jkcs.2003.47.4.345
Ho Sik, K
,
Kyung Ok, C
,
&
Woo Sung, L
2003,
Synthesis and Tautomerism of Novel Quinoxalines (Part II),
Journal of the Korean Chemical Society,
vol. 4,
no. 4,
Retrieved from http://dx.doi.org/10.5012/jkcs.2003.47.4.345
[1]
K Ho Sik
,
C Kyung Ok
,
and
L Woo Sung
,
“Synthesis and Tautomerism of Novel Quinoxalines (Part II)”,
Journal of the Korean Chemical Society,
vol. 4,
no. 4,
Aug
2003.
Ho Sik, Kim
and
,
Kyung Ok, Choi
and
,
Woo Sung, Lim
and
,
“Synthesis and Tautomerism of Novel Quinoxalines (Part II)”
Journal of the Korean Chemical Society,
4.
4
2003:
Ho Sik, K
,
Kyung Ok, C
,
Woo Sung, L
Synthesis and Tautomerism of Novel Quinoxalines (Part II).
Journal of the Korean Chemical Society
[Internet].
2003.
Aug ;
4
(4)
Available from http://dx.doi.org/10.5012/jkcs.2003.47.4.345
Ho Sik, Kim
,
Kyung Ok, Choi
,
and
Woo Sung, Lim
,
“Synthesis and Tautomerism of Novel Quinoxalines (Part II).”
Journal of the Korean Chemical Society
4
no.4
()
Aug,
2003):
http://dx.doi.org/10.5012/jkcs.2003.47.4.345