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Partial Synthesis of Fibrostatins
Partial Synthesis of Fibrostatins
Journal of the Korean Chemical Society. 2003. Feb, 47(1): 47-58
  • Published : February 20, 2003
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Lee, Kwan Hee
Moore, Harold w.

Abstract
Fibrosstatins, which were isolated from the culture broth of Streptomyces catanulae subsp. griseospora, are naphthoquinones which can work as alkylating agents. It is important to synthesize these quinone compounds for the study of their biological activities. In this paper, an efficient method, Hooker oxidation, to control the regiochemistry in the synthesis of fibrostatin B is reported.
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