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Synthesis of New 2-Quinazolylacetonitrile Derivatives
Synthesis of New 2-Quinazolylacetonitrile Derivatives
Journal of the Korean Chemical Society. 2001. Dec, 45(6): 532-537
  • Published : December 00, 2001
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Kim, Jung Hwan
Min, Kyung Su

Abstract
2-Quinazolylacetonitrile derivatives containing H-chelate have been synthesized from 2-cyanomethylquinazoline using electrophiles such as 4-chloroquinazoline, 4-chloro-2-phenylquinazoline, 4,6-dichloropyrimidine, 4,6-dichloro-2-phenylpyrimidine, 4,6-dichloro-5-phenylpyrimidine, 2-chloroquinoxaline, 1,3-dichloroisoquinoline, 2,6-dichloropyrazine, 2-chloropyrazine and 4,6-dichloro-2,5-diphenylpyrimidine. These H-chelates may serve as a polymethine chromophore system. Structures of the target molecules were identified by spectral methods.K010606