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Antitumor Evaluation of Epigallocatechin Gallate by Colorimetric Methods
Antitumor Evaluation of Epigallocatechin Gallate by Colorimetric Methods
Journal of the Korean Chemical Society. 1998. Aug, 42(4): 411-415
  • Published : August 00, 1998
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Baek, Soon Ok
Kim, Il Kwang
Baek, Seung Hwa
Han, Du Seok

Abstract
In the present study, we were evaluated cytotoxic effects of epigallocatechin gallate in human skin melanoma cells such as HTB-69. The light microscopic study showed morphological changes of the treated cells. Disruptions in cell organelles were determined by colorimetric methods; 3-(4,5-dimethyl thiazol-2-yl)-2,5diphenyl-2H-tetrazolium bromide (MTT) assay, neutral red (NR) assay and sulforhodamine B protein (SRB) assay. These results suggest that epigallocatechin gallate retains a potential antitumor activity.