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Synthesis of New 5-Benzyl-4-cyanomethyl-2-methylpyrimidine Derivatives
Synthesis of New 5-Benzyl-4-cyanomethyl-2-methylpyrimidine Derivatives
Journal of the Korean Chemical Society. 1996. Apr, 40(4): 249-253
  • Published : April 00, 1996
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Kim, Jung Hwan
Han, Mun Su

Abstract
The synthesis of new 5-benzyl-4-cyanomethyl-2-methylpyrimidine derivatives (5) containing chloro, methoxy, ethoxy, phenoxy and anilino groups at 6-position on the pyrimidine ring were prepared from 5-benzyl-4-chloro-2-methylpyrimidine derivatives (3) and tert-butylcyanoacetate. The derivatives of 5-benzyl-4-chloro-2-methylpyrimidine (3) containing chloro, methoxy, ethoxy, isopropoxy, phenoxy and anilino groups at 6-position on the pyrimidine ring were prepared from 5-benzyl-4,6-dichloro-2-methylpyrimidine (2).????????????6??K?޿??????��????