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Synthesis of Vinyl Sulfone-tethered Proline Derivatives as Highly Selective Cathepsin S Inhibitors
Synthesis of Vinyl Sulfone-tethered Proline Derivatives as Highly Selective Cathepsin S Inhibitors
Bulletin of the Korean Chemical Society. 2014. Feb, 35(2): 345-346
Copyright © 2014, Korea Chemical Society
  • Received : November 23, 2013
  • Accepted : November 27, 2013
  • Published : February 20, 2014
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About the Authors
Mira Kim
College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.
Jiyoung Jeon
Department of Drug Discovery, Hanmi Research Center, Gyeonggi-do 445-813, Korea.
Jongouk Baek
Department of Drug Discovery, Hanmi Research Center, Gyeonggi-do 445-813, Korea.
Jaeyul Choi
Department of Drug Discovery, Hanmi Research Center, Gyeonggi-do 445-813, Korea.
Eun Ju Park
College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.
Jiyeon Song
Department of Drug Discovery, Hanmi Research Center, Gyeonggi-do 445-813, Korea.
Hyojeong Bang
College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.
Kwee Hyun Suh
Department of Drug Discovery, Hanmi Research Center, Gyeonggi-do 445-813, Korea.
Young Hoon Kim
Department of Drug Discovery, Hanmi Research Center, Gyeonggi-do 445-813, Korea.
Jongmin Kim
College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.
Doran Kim
College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.
Kyung Hoon Min
College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.
Kwang-Ok Lee
Department of Drug Discovery, Hanmi Research Center, Gyeonggi-do 445-813, Korea.

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Acknowledgements
We thank Eun Young Kim, Tae Hun Song, and Dr. Hankyung Kim for their assistance in the pharmacokinetic studies. This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean Government (2011-0007305), and partially by the Chung-Ang University Excellent Student Scholarship in 2013.
References
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